Welcome to UChicago PCCM Research!
Research defining the mechanisms, diagnosis, and treatment of lung disease and critical illness is a central mission of our group. This research is conducted in our clinical facilities as well as our basic research laboratories. Investigators are actively engaged in studying lung biology and cellular function related to critical illness, using techniques of cell and molecular biology, immunology, and genetics. Large and innovative clinical studies are also in place, with questions related to diagnosis and management of diverse diseases answered by accomplished clinical scientists observing individual patients and patient populations.
The strength of our research enterprise derives from the high degree of collaboration between basic and clinical scientists, and the joining of faculty and research associates with diverse training, expertise, and interests. The PhD, MD, and MD-PhD investigators in our group sustain this multi-faceted and dynamic approach to biomedical research. The essence of this activity is to ask important questions, and to answer them with whatever means are necessary—often employing the means of both clinical and basic science. The flow of ideas and findings is from bedside to bench and back, with each discovery adding to new questions requiring creative approaches to answer them. This exciting atmosphere provides abundant learning opportunities for students at every level of training, and we have successfully incorporated college, medical, and graduate students; post-doctoral scientists; residents; and fellows in our many programs.
News
New PNAS publication!
Congratulations to Zhengjie and the Fang lab!!
Targeted polyelectrolyte complex micelles treat vascular complications in vivo. Now published in PNAS!!
Zhengjie Zhou1,2, Chih-Fan Yeh2,3, Michael Mellas1, Myung-Jin Oh2, Jiayu Zhu2, Jin Li2, Ru-Ting Huang2, Devin Harrison2.4, Tzu-Pin Shentu2, David Wu2, Michael Lueckheide1, Lauryn Carver1,2, Eun Ji Chung1, Lorraine Leon1, Kai-Chien Yang3, Matthew V. Tirrell1,4,5,*, Yun Fang2,4*
- Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA
- Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA
- Division of Cardiology, Department of Internal Medicine and Cardiovascular Center, National Taiwan University Hospital, Taipei, Taiwan.
- Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL60637, USA.
- Argonne National Laboratory, Lemont, IL 60439, USA
New publication in PNAS by the Fang group!
Congratulations to Zhengjie!
Targeted polyelectrolyte complex micelles treat vascular complications in vivo. Accepted in PNAS!!
Zhengjie Zhou1,2, Chih-Fan Yeh2,3, Michael Mellas1, Myung-Jin Oh2, Jiayu Zhu2, Jin Li2, Ru-Ting Huang2, Devin Harrison2.4, Tzu-Pin Shentu2, David Wu2, Michael Lueckheide1, Lauryn Carver1,2, Eun Ji Chung1, Lorraine Leon1, Kai-Chien Yang3, Matthew V. Tirrell1,4,5,*, Yun Fang2,4*
- Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA
- Department of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL 60637, USA
- Division of Cardiology, Department of Internal Medicine and Cardiovascular Center, National Taiwan University Hospital, Taipei, Taiwan.
- Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL60637, USA.
- Argonne National Laboratory, Lemont, IL 60439, USA